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Monday, November 16, 2015

Software and cellular repair - both offend the cult of Darwin's simplistic view of life.

Complex systems do not engage in maintenance due to 'chaos'.

by StFerdIII

 

Autopoiesis is a biological fact. Organisms must repair themselves or they die and the species becomes extinct [general law of entropy]. There are at least 148 known genes dedicated to DNA repair, using at least 14 known different methods, carrying out up to a million repair events per cell per day. Your car, your chair, your coffee cup do not self-repair; do not regenerate cells [the brain replaces billions each day]; nor do they manage their internal software code. Mutations or bugs, destroy software. Ask an IT engineer. Most the time spent with software code is spent in repairing, managing and maintaining – not coding.

Not only does the system complexity of humans allow for maintenance, it also provides redundancy and failover. A good IT engineer will know these concepts. They are mandatory for system development and to perform load balancing and ensure availability. Organisms have the same capability – built directly into their software code. For example, every production pathway for every molecular component in a cell has a corresponding degradation pathway so that redundant, used and/or damaged molecules can be broken down and the parts recycled. This feat of engineering is impossible to construct with random chance.

The human body is so well engineered that there are even programmed cell death mechanisms to remove unwanted cells from a developmental pathway (apoptosis) and to cleanly dispose of malfunctioning or injured cells (necrosis). Damage to these degradation pathways often leads to disease and death because cells and tissues become clogged with molecular rubbish.

Again we see the law of entropy at work – all systems, closed, hybrid, or open in any manner will simply degrade and die. The only way to keep a system alive is to maintain it, and clear out the mutations, which the cult of Darwin ignorantly believes causes advancement, in spite of the physical and observational fact that it generates a loss of information and system capability.

It is all or nothing, no 'evolution' of a cell is even remotely possible

The universality of autopoiesis highlights the fact of all or nothing within the software code of life. You need all of a cell's singular complexity. Pieces of it are useless in isolation. This also a fact of biology beyond dispute.

In Kirschner and Gerhart’s book The Plausibility of Life: Resolving Darwin’s Dilemma, in which they announce the first ever theory—called facilitated variation—of how life works at the molecular level, they identify two basic components:

    -conserved core processes of cellular architecture, metabolic function and body plan organization; and

    -modular regulatory mechanisms that are built in special ways that allow them to be easily rearranged into new combinations to generate new and variable phenotypes.

    Concerning the conserved core processes, they say,

    Core processes may have emerged together as a suite, for we know of no organism today that lacks any part of the suite … The most obscure origination of a core process is the creation of the first prokaryotic cell. The novelty and complexity of the cell is so far beyond anything inanimate in the world of today that we are left baffled” (pp. 253–256).

The central message of Kirschner and Gerhart’s theory is that not genes but the cell, with its highly conserved architecture, machinery and regulatory circuitry, is the centrepiece of life and heredity. When these ideas are combined—that the cell as a whole is the functional entity, that cell structure and function is highly conserved, that its origination as a whole entity has no naturalistic explanation, and that the “suite of core processes” is universal—this clearly supports the universality of autopoiesis.”

 

Autopoiesis and cell complexity make a mockery of the cult of Darwin.